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Search Results for " annexin i "

3

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP2083	Ac9-25
	N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. Acts as a formyl peptide receptor 1 (FPR1) ligand and stimulates neutrophil NADPH oxidase activation.
T75813	Ac9-25 TFA
	Ac9-25 TFA, 膜联蛋白 I N 端肽，作为甲酰肽受体(FPR)的激动剂，能激活中性粒细胞NADPH氧化酶通过FPR。
T70962	MHY219
	MHY219 is a novel HDAC inhibitor. MHY219 induces apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells. MHY219 was shown to enhance the cytotoxicity on DU145 cells (IC50, 0.36 μM) when compared with LNCaP (IC50, 0.97 μM) and PC3 cells (IC50, 5.12 μM). MHY219 showed a potent inhibition of total HDAC activity when compared with SAHA. MHY219 increased histone H3 hyperacetylation and reduced the expression of class I HDACs (1, 2 and 3) in prostate cancer cells. M...

化合物

Cat.No: TP2083

Cat.No: T75813

Cat.No: T70962

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00766	ANXA1 Protein, Human, Recombinant Chromobindin-9,Phospholipase A2 <...	Human	E. coli
	Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity. Annexin A1 also has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis, and tumorigenesis and cancer development. ANXA1 is strongly expressed on th...
TMPK-00799	ANXA1 Protein, Mouse, Recombinant (His) Calpactin-2,LPC1,Annexin-1,An...	Mouse	E. coli
	Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Mouse, Re...
TMPK-00768	ANXA1 Protein, Human, Recombinant (His) Annexin A1,Calpactin I	Human	E. coli
	Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Human, Re...
TMPK-01291	ANXA1 Protein, Cynomolgus, Recombinant (His) Lipocortin I,Calpactin-2...	Cynomolgus	E. coli
	Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Cynomolgu...
TMPH-00938	ANXA5 Protein, Human, Recombinant (His) ANXA5,Annexin A5,Annexin...	Human	P. pastoris (Yeast)
	This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. ANXA5 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 37.8 kDa and the accession number is P08758.
TMPJ-00799	ANXA2 Protein, Human, Recombinant ANXA2,Calpactin I Heavy Chain,ANX...	Human	E. coli
	Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression reduce of ANXA2 is associated with osteosarcoma metastases. ANXA2 functions as an autocrine factor, it can increases osteoclast formation and bone resorption. ANXA2 is involved in muscular dystrophies. In humans, the up-regulation of ANXA2 is related with colon adenocarcinoma cell...
TMPY-01926	S100A10 Protein, Human, Recombinant (His) ANX2L,S100 calcium binding prote<...	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S1 proteins have been implicated in a variety of int...

重组蛋白

ANXA1 Protein, Human, Recombinant

Cat.No: TMPJ-00766

Species: Human

Expression System: E. coli

ANXA1 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00799

Species: Mouse

Expression System: E. coli

ANXA1 Protein, Human, Recombinant (His)

Cat.No: TMPK-00768

Species: Human

Expression System: E. coli

ANXA1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01291

Species: Cynomolgus

Expression System: E. coli

ANXA5 Protein, Human, Recombinant (His)

Cat.No: TMPH-00938

Species: Human

Expression System: P. pastoris (Yeast)

ANXA2 Protein, Human, Recombinant

Cat.No: TMPJ-00799

Species: Human

Expression System: E. coli

S100A10 Protein, Human, Recombinant (His)

Cat.No: TMPY-01926

Species: Human

Expression System: E. coli

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